Effective removal of middle molecular toxins AutoSub plus – Maximising substitution volumes in haemodiafiltration (HDF) for high convective removal of middle molecules, significantly reducing

While other systems check and adjust the transmembrane pressure (TMP) in defined time intervals, AutoSubplus measures and evaluates the conditions directly inside the filter several times per minute. For these patients we have intensified our research and developed the MIXED HDF option for the 5008 CorDiax. The 5008 dialysis machine enables the simultaneous delivery of post- and pre-dilution volumes — the so called MIXED HDF. It enables dynamic and highly-sensitive monitoring of the venous pressure by combining arterial and venous pressure signals with an adaptive algorithm. 5008S CorDiax is to deliver Cardioprotective Haemo­ dialysis with advanced safety for reduced cardiovascular complications and mortality. This aims to give the nursing staff more time to react appropriately to critical pressure changes. As a result, substitution volumes can be maximized individually for every patient without any user interaction. With a standard setup of a 5008 CorDiax or 5008S CorDiax you can already perform HighVolumeHDF. It is not only the advanced treatment options that makes the 5008 series unique, but also its eco-friendliness: with the 5008 CorDiax series, Fresenius Medical Care supports the sensible and sustainable use of resources by saving dialysate, water and energy. Based on the highly reliable two stage filtration process ONLINEplus facilitates the online production of sterile and nonpyrogenic substitution fluid very cost-efficiently.

By clicking on the button "Accepted and Confirmed" you assure that you have taken note of this information and that you are a healthcare professional. The 5008 CorDiax enables the simultaneous delivery of post- and pre-dilution volumes — the so called MIXED HDF. Still, the user remains responsible for patient safety at all times during treatment. Although most patients will reach sufficient substitution volumes with AutoSubplus, there might be patients with unfavorable conditions unable to reach sufficiently high convective volumes.

Our innovative blood lines are developed based on the idea that HighVolumeHDF shall be as easy and safe to handle as HD. Fresenius Medical Care uses cookies on this website to enhance the user experience and provide the best possible service. With its two substitution pumps, the convective transport can be increased by adding a pre-dilution share to avoid the risk of hemoconcentration or to compensate for low blood flows.
The innovative technology behind it is based on a dynamic signal analysis of pressure pulses. A close up of two substitution pumps that make Mixed HDF possible. The 4008S classix combines quality hemodialysis (HD) treatment with proven reliability and efficiency. For details see our privacy policy. This in turn leads to significant cost savings. The mixing ratio, the Na concentration and the bicarbonate concentration may … VAM also includes an alarm management system: an alarm is activated if the monitored signals show exceptional or abnormal variations to the previous pressure profile. Hemodialysis machines and devices. This added to the workload of the nursing staff and deterred dialysis-centers from using HDF.

With the new AutoSubplus function of the 5008 and the 5008S HighVolumeHDF becomes as simple and reliable as HD without any additional need for user interaction. The 5008 Therapy System was developed to fulfil cur rent challenges in haemodialysis: continually incr easing patient numbers with a growing share of medically challenging patients, combined with often limited funding and staff. The 5008 CorDiax and 5008S CorDiax offer as standard in all machines a sophisticated safety feature to minimize the risk of external blood loss: VAM is a unique and intelligent safety feature. VAM has been developed to support the health-care professionals in early detection of venous needle dislodgement. With a standard setup of a 5008 CorDiax or 5008S CorDiax you can already perform HighVolumeHDF. 6008 … In order to achieve the full benefits of HDF therapy large convective volumes in post-dilution mode are required. By continuing to browse the website, you consent to our use of cookies. Historically, the required amounts of substitution fluid had to be provided in infusion bags.
In order to give more patients access to the benefits of HDF, we have developed a dialysis system, which prepares the substitution fluid directly at the bedside – The ONLINEplus system. The hemodialysis system 5008 is designed for both acetate dialysis and bicarbonate dialysis.

With its two substitution pumps, the convective transport can be increased by adding a pre-dilution share to avoid the risk of hemoconcentration or to compensate for low blood flows. The 5008 Therapy System therefore offers a combination of convincingly easy handling with a thoughtful use of the dialysis-relevant …

Fresenius Medical Care 6008 CAREsystem and 5008 CorDiax machines enable HighVolume HDF as a standard in dialysis. It is not only the advanced treatment options that makes the 5008 series unique, but also its eco-friendliness: with the 5008 CorDiax series, Fresenius Medical Care supports the sensible and sustainable use of resources by saving dialysate, water and energy. The medical device and therapy related information on this website is aimed exclusively at healthcare professionals.

AutoSubplus — Automatically maximizing substitution volume for HighVolumeHDF.

If an alarm is emitted, the blood pump is stopped immediately and the venous clamp is closed.

In this way, VAM is designed to indicate sudden, small drops in venous pressure of approximately 15 mmHg, even when the venous pressure does not exceed the lower alarm limit. Host: fresmedi-corporate-prod-pub-i-0674c154c6df6cdca, Treatment options for kidney disease (CKD), Very precise information on the conditions in the dialyzer is available - not just across the membrane but also along the blood flow pathway, Several checks per minute enable the continuous optimization of the substitution rates, The system is automatically activated at the start of treatment, AutoSubplus — Automatically maximizing substitution volume for HighVolume, Venous Access Monitoring (VAM) — Optimized monitoring of the venous path, Extensive amounts of substitution fluid for HDF available, No more need for ready-made rinse solutions: priming, reinfusion and bolus with ONLINE fluid in all treatment modes (also in HD), AutoFlow automatically adjusts the dialysate flow rate to the effective blood flow rate during treatment, Substantial saving of water, waste water, concentrates and energy, leading to significant cost reductions, Automatic selection of AutoFlow factor based on treatment mode, always accomplishing an optimal ratio between economic considerations and treatment quality, EcoFlow for minimized dialysate and energy consumption during preparation and after reinfusion while avoiding bacterial growth. Not all products are cleared or available for sale in all countries. 1 In accordance with ISO 23500-5 and ISO 11663:20092 Safety advice: It is recommended that you stock sodium chloride in case it might be required. The 5008 Therapy System A Vision turned into Reality. Online hemodiafiltration was born. In the past many users were concerned that these high volumes may lead to excessive hemoconcentration and subsequently high transmembrane pressures if the treatment settings are not continuously monitored and adjusted. AutoSubplus supports the nephrologist in establishing HighVolumeHDF as standard therapy. In particular during HighVolumeHDF where high blood flows are aspired for, monitoring of the venous access is essential as a blood loss would become critical within a very short time.